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Best Mexican Food in Northeast Portland

Oaxacan food on 42nd Avenue since 2006

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Gloria and Abraham

Gloria and Abraham

Abraham and Gloria both come from the Region Mixteca of Oaxaca. They opened Santo Domingo Taqueria in 2006, and the two of them now focus on the restaurant.
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Carnitas tacos

Carnitas tacos

Get the carnitas. We put a little crisp on the tortillas and on the meat, and a spoonful of avocado salsa goes on top.
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Tortillas on weekends

Tortillas on weekends

Come Saturday or Sunday and you'll get our homemade corn tortillas. Put them under al pastor, lengua or chorizo.
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Order at the counter, eat outside

Order at the counter, eat outside

We have covered picnic tables out front, and your dog is welcome there. Order at the counter, then pick up your food and sit wherever you like.

The patio

Simply amazing!! The service was fantastic and extremely friendly, too. Out door seating was available, which was perfect since it was a Georgia’s day! I ordered the torta de asada and beef taquitos and... well I almost ate the plates, too. Both were so amazingly tasty. The beans in the torta were perfection and the guacamole on the taquitos was extremely good. Reasonably priced and the perfect meal after a10 hour plane ride! I highly recommend this place! Can’t wait to be back!!

Jeff A.

First off, they have good tortillas, which is kind of rare to find. The carnitas to me are the star of the show, crisp and well seasoned with the avocado-based salsa really setting everything off. The tripas are another fave. Agua de Tamarindo also hits a nice balance of tart and not-too-sweet. Reliably delicious, and perfect for having a taco picnic. A Portland gem.

Amy F.

Fantastic tacos, some of the best available close in in Portland. They actually take the time to put a little crisp on the tortillas, and on the carnitas! They also give you a little avocado salsa on the carnitas, a really nice touch you don’t see everywhere. My go to. It hits!

Evan L.

I came in and it was really crowded. Everyone was kind and accommodating. I got the carnitas nachos. The amount of meat we got was incredible. Chips laid perfectly beneath. Onions, tomatoes, refried beans, cheese and choice of sauces. Green and red were both delicious. We ate them so fast I forgot to take a picture. Will be returning! I’m a fan.

Meaghan S.

Santo Domingo is a small eatery that serves excellent Mexican food including some of the best carnitas I've had at this writing. Their tacos are loaded with savory meat with a bit of tomato, onion, cilantro and guacamole. The texture and flavor of the carnitas in on point. The burritos are large for those with hungry appetites. Santo Domingo has indoor and outdoor seating. There's three parking spots in the tiny lot in front. Otherwise there's street parking. Check out my profile for more…

Michael K.

Santo Domingo Taqueria Rewards

Santo Domingo Taqueria Rewards

Join our rewards program, earn points every time you order online and redeem your points for free food!
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Frequently Asked Questions

What are your most popular dishes?

Santo Domingo Taqueria is known for casual Mexican food. Our most popular dishes include:

  • Enchiladas de Mole: Three enchiladas with a choice of meat, covered in rich house mole sauce and topped with sesame and queso fresco, served with rice and beans.
  • Al Pastor, Chorizo, Tripa or Buche Taco: A homemade corn tortilla holds a choice of marinated al pastor pork, chorizo, tripa, or buche, topped with onion, cilantro, and salsa.
  • Bacon Breakfast Burrito: Crispy bacon, scrambled eggs, fresh-cut potatoes, and cheese are wrapped in a flour tortilla.
  • Super Nachos: Tortilla chips piled with a choice of meat, beans, cheese, sour cream, pico de gallo, and guacamole.
  • Quesadilla with Meat: Melted cheese and guacamole are folded into a flour tortilla with a choice of meat.
  • Chilaquiles: Crispy tortilla chips simmered in green salsa, topped with onion, cilantro, and queso fresco, and served with 3 eggs.

Check out our full menu.

What are you known for?

We’re known for Mexican tacos, breakfast burritos, and mole dishes, alongside seafood plates and vegetarian options in Northeast Portland.

  • Mexican Food: Mexican favorites range from tacos and breakfast burritos to mole enchiladas, tamales, and seafood plates. Examples include Carne Asada Taco, Cactus Breakfast Burrito, Enchilada De Mole, Tamales Plate, and Mojarra Plate.
  • Latin American Food: This Mexican-focused menu brings together tortas, chilaquiles, cactus tacos, and steak with onions. Examples include Milanesa Torta, Chilaquiles W/ Egg, Tacos De Nopales (Cactus), and Bistec Encebollado.
  • Burritos: Burrito fillings span carne asada, carnitas, seafood, beans and cheese, and breakfast options with cactus or chorizo. Examples include Carne Asada Burrito, Carnitas Burrito, Shrimp Burrito, Bean & Cheese Burrito, Cactus Breakfast Burrito, and Chorizo Breakfast Burrito.
  • Tacos: Tacos feature meat, fish, and vegetable options, with soft-shell and hard-shell formats also available. Examples include Al Pastor Taco, Fish Taco, Tacos De Nopales (Cactus), Lengua Taco, Soft Shell Taco, and Hard Shell Taco.
  • Breakfast: Breakfast pairs meat or vegetable burritos with huevos rancheros and chilaquiles topped with eggs. Examples include Bacon Breakfast Burrito, Veggie Breakfast Burrito, Chorizo Breakfast Burrito, Huevos Rancheros, and Chilaquiles W/ Egg.

Additionally, explore Chicken, Fries, Quesadillas, Seafood, Enchiladas, Fish, Drinks, Tortas, Dinner, and Salads.

What meals do you serve?

We serve Breakfast, Lunch, and Dinner

Do you offer delivery & takeout?

Yes, we offer Takeout and Delivery

Do you offer catering?

Yes! Santo Domingo Taqueria offers catering for parties, office lunches, family gatherings, and other events.

Visit our catering page for more information.

What payment methods do you accept?

When you order online, we accept credit cards (Mastercard, Visa, American Express, Discover), Apple Pay, and Google Pay.

Services & amenities

Is your restaurant wheelchair accessible? Yes, our restaurant is wheelchair accessible.

What areas do you serve?

We serve the following areas: Alameda, Portland, Vancouver, Champ, Fir, Graham, Maywood Park, Beaumont-Wilshire, Concordia, McLoughlin, Faloma, Alameda, Image, Ladd Circle, Russellville, Woodlawn, King, Grant Park, Roseway, and Cully Association Of Neighbors.

Our location

Map showing the location of Santo Domingo Taqueria on 5447 NE 42nd Ave in Portland
Santo Domingo Taqueria

Portland, OR

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